The Peptide Guide
GLP-1 / Metabolic

Mazdutide: dose range, storage & handling reference

Also known as: IBI362, LY3305677, GLP-1/glucagon dual agonist

Quick answer

What is Mazdutide?

A GLP-1 + glucagon dual agonist in trials for weight loss with an added energy-burn component.

Mazdutide at a glance

Dose range referencedResearch literature commonly references escalating weekly amounts studied across roughly the ~3–9 mg/week range in trials
Studied forMetabolic and weight-management research
Route referenced in researchSubcutaneous (research)
Half-life~4–7 days (reported)
StorageStore lyophilized powder refrigerated (2–8°C) and protected from light; once reconstituted, keep refrigerated and use within the timeframe supported by stability data.

The dose range above describes figures referenced in research literature. It is not a recommendation.

What Mazdutide is stacked with in research

Referenced in research as a single dual-agonist molecule; combining with other incretin agents is not standard in the literature.

Side effects observed in research

  • Nausea
  • Reduced appetite
  • Diarrhea
  • Gastrointestinal upset

Reconstituting Mazdutide

Concentration is vial contents divided by water added, whatever the compound: a 5 mg vial with 2 mL of bacteriostatic water gives 2.5 mg/mL. The step-by-step reconstitution guide works through the arithmetic, and the free calculator below returns exact syringe units.

This is a reference entry. An expanded profile — mechanism, cited literature, protocol tables and reconstitution math — is being added across the library.

Skip the Mazdutide math

Enter vial size, water volume, and target dose — the free calculator returns concentration, injection volume, and exact U-100 syringe units.

Calculate

Convert vial, water, and dose into syringe units.

Free calculator →

Track

Log doses, schedules, and sources in one place.

Get the free app →

Source in Canada

COA-documented research compounds, sourced from Canada.

RegenBioSignals →

Referral partner — we may earn a commission.

Related research peptides

Browse all GLP-1 / Metabolic peptides or start with the beginner’s guide to research peptides.