Longevity & skin research
Anti-Aging Protocol (Epitalon + GHK-Cu)
Why this combination exists
The two compounds are paired because they act on different layers of the ageing question. Epitalon is studied for its effect on telomerase and gene expression — the machinery that maintains chromosome ends — and the Russian research behind it was designed as short, repeated courses rather than continuous use. GHK-Cu is a copper-carrying tripeptide studied for skin remodelling, collagen signalling and wound repair, where the literature references daily administration over several weeks.
Their rhythms are the point: Epitalon runs as a 10–20 day course one to three times a year, GHK-Cu as 3–4 week daily cycles. A referenced pattern nests the Epitalon course inside a GHK-Cu cycle, so the short-course compound and the daily compound are tracked together but never confused for each other.
Literature-referenced schedule
| Component | Referenced schedule |
|---|---|
| Epitalon | 5–10 mg once daily for a 10–20 day course (literature reference); courses repeated 1–3× per year, not run continuously |
| GHK-Cu (injectable) | 1–2 mg once daily, 3–4 week cycles referenced — or topical daily application over 8–12 weeks in cosmetic studies |
| Cycle structure | Start GHK-Cu; begin the Epitalon course inside that cycle; break for at least as long as the cycle before repeating |
Reconstitution notes
Epitalon doses are large by peptide standards, so use less water: 10 mg Epitalon + 1 mL BAC water = 10 mg/mL, and a 5 mg dose is 0.5 mL — 50 units; with 2 mL of water the same dose is a full 100-unit syringe. GHK-Cu: 10 mg + 2 mL BAC water = 5 mg/mL, so 1 mg is 0.2 mL — 20 units. GHK-Cu solution is distinctly blue from the copper; keep the two vials and syringes separate and never draw them into one. Both refrigerate reconstituted and are used within weeks.
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Peptides in this protocol
Epitalon
A four-amino-acid peptide based on a pineal-gland extract, studied for effects on telomerase — the enzyme that maintains the caps on chromosomes.
Full research profile →
Skin & LongevityGHK-Cu
A copper-binding tripeptide studied for skin remodeling, wound healing and anti-aging in topical and research use.
Full research profile →
Source in Canada
COA-documented research compounds, sourced from Canada.
RegenBioSignals →Referral partner — we may earn a commission.
Frequently asked questions
Why is Epitalon run as a course and not daily like GHK-Cu?
Because that is how the research was designed. The original Russian protocols used 10–20 day courses repeated a few times a year, and the literature has no continuous-use data. GHK-Cu studies, by contrast, apply the compound daily for weeks and measure over 8–12 weeks.
Can Epitalon and GHK-Cu go in the same syringe?
Referenced protocols keep them separate. Their schedules differ (a short course versus a daily cycle), the GHK-Cu solution carries copper, and mixing makes it impossible to adjust one without the other.
Is topical GHK-Cu an alternative to injecting it in this stack?
The cosmetic literature is almost entirely topical, so yes for skin-focused research; the injectable reference exists for systemic study. Both appear in referenced anti-aging protocols, and the choice depends on what is being measured.